Ball security is a quarterback's No. 1 priority.
That's why ball-handling drills are an important component of quarterback training. They help develop the hand-eye coordination and grip strength needed to avoid muffed snaps and bad exchanges.
Eli Manning is apparently freakishly good at such drills:
Judging by the fact the other New York Giants quarterbacks had to do Push-Ups after Eli finished, it's clear that the players regularly compete at this drill. Based on Eli's ball-handling wizardry, we don't expect him to lose anytime soon.